Endocrine Abstracts

Background and aims: Progradient course of diabetes mellitus as well as inevitable onset and progression of its late complications having polyorganic character, causing polymorbidity and high mortality of the patients underlie medical–social significance of the problem.Materials and methods: We examined 784 persons (36% men and 64% women, mean age 53 and 51 years respectively) at high risk of diabetes mellitus onset and progression being screened in...

Introduction: Diabetes is the most common endocrine disease in the world. Persistent hyperlipidemia in type 2 diabetes is accompanied by damage to various organs, on the basis of which generalized changes in the microvasculature lie. In patients with diabetes mellitus with chronic kidney disease, dyslipidemia can be aggravated with hyperglycemia and insulin resistance. Control of dyslipidemia is an important therapeutic goal, since normalization of lipid metabolism and glycemi...

The aim: To evaluate the results of Questionnaire by Comprehensive Symptom Profile Diabetes Mellitus hypoglycemia (CSP-DM-HypoGl) nodule in type 2 diabetes patientsMaterial and methods: Under our supervision in the departments of the Center of Endocrinology of PH Ministry of RUz in the period from September 2016 for December, to 2017, 20 patients were observed with DM 2, men – 9, women-11; 54.5±1.5 m/61,6±1.8 w years old. The remoteness of...

The aim: To evaluate the risk factors for symptomatic hypoglycemia (SG) over 4 years of intensive insulin treatment (IIT) and combined therapy (CT) in type 2 diabetes.Material and methods: Under our supervision in the departments of the Center of Endocrinology of PH Ministry of RUz in the period from September 2016 for December, to 2017, 20 patients were observed with DM 2, men – 9, women – 11; 54.5±1.5 m/61.6±1.8 w years old. The rem...

Introduction: Malignant tumors of the thyroid gland are common in the field of endocrinology as an oncological disease. The diagnosis of thyroid cancer (TC) is based on sonographic and cytological methods. The widespread use of TI-RADS classification and the Bethesda System for Reporting Thyroid Cytopathology proposed by the American College of Radiology (ACR) and the U.S. National Cancer Institute (NCI) relatively significantly increases diagnostic accuracy. In this study dia...

Introduction: Diabetes Mellitus (DM) is one of the Global pandemics despite to new knowledges and methods of prevention and therapy intensively increased among children, adolescents and adults. Many studies shown the role of the gastrointestinal microbiocenosis in the development and clinical future of DM. Gut microbiota produce numerous bioactive molecules, which can act locally and secreted into bloodstream. The aim of our study were evaluation of gut microbiota in children ...

Introduction: The purpose of this work was monitor the frequency of determination and compare the levels of parathyroid hormone in blood plasma in people on programmed hemodialysis.Material and methods: Data from medical records of 465 patients on programmed hemodialysis who were admitted to the Republican Centre of Nephrology and Kidney Transplantation were analyzed. Patients according to reason of end stage of renal failure were divided into 3 groups d...

The work was initiated to comparatively study pregnancy outcomes in patients with type I diabetes mellitus (DMI) with self-control skills and without them.We examined 50 patients with DMI aged from 20 to 29 (mean age 24±3.2 years) ranging from those with newly diagnosed disease to those with DMI duration under 12 years. Glycemia and HBA1c levels were measured to assess carbohydrate metabolism.40 patients with planned pregnancy...

The work was initiated to study peculiarities of pregnancy in patients with prepubertal onset of type 1 diabetes mellitus (T1DM).We examined 22 patients with prepubertal onset of T1DM. Glycemia and HbA1c levels were measured to assess carbohydrate metabolism. All patients were examined in compliance with protocol of management for patients with pre-gestational diabetes.Mean age of the examinees, primagravidas, was 21.4±4.7, th...

Background: Obesity is worldwide epidemics and the main risk factor for many diseases. Traditional methods of prevention and treatment of obesity often unfavorable and patients undergo to alternative treatment such as bariatric surgery. To better understanding the pathogenesis of obesity, we aimed to analyse the main abnormalities in blood serum in patients accepted to bariatric surgery.Material and Methods: 27 patients (13 men and 14 women) with obesity...